Domains and outcome measures for the assessment of limited cutaneous systemic sclerosis: an international collaborative scoping review.

ABSTRACT:

Objectives

The aim of this study was to comprehensively identify instruments within relevant domains employed to assess lcSSc since the endorsement of its consensus definition in 1988. The overall objective is to inform the creation of a Combined Response Index for Scleroderma Trials Assessing lcSSc (CRISTAL).

Methods

MEDLINE and Embase were searched using terms selected to comprehensively retrieve titles and abstracts mentioning both lcSSc and dcSSc, along with those only mentioning lcSSc, SSc sine scleroderma, limited SSc and/or CREST/CRST. Because our initial assessment of the literature revealed that very few studies included only lcSSc subjects, we also assessed literature that included both cutaneous subsets. A total of 3964 titles and abstracts were screened by two re

SUBMITTER: Lescoat A 

PROVIDER: S-EPMC9338174 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature