Metagenomic analysis reveals associations between salivary microbiota and body composition in early childhood.

ABSTRACT: Several studies have shown that body mass index is strongly associated with differences in gut microbiota, but the relationship between body weight and oral microbiota is less clear especially in young children. We aimed to evaluate if there is an association between child growth and the saliva microbiome. We hypothesized that associations between growth and the saliva microbiome would be moderate, similarly to the association between growth and the gut microbiome. For 236 toddlers participating in the New Hampshire Birth Cohort Study, we characterized the association between multiple longitudinal anthropometric measures of body height, body weight and body mass. Body Mass Index (BMI) z-scores were calculated, and dual-energy x-ray absorptiometry (DXA) was used to estimate body composition

SUBMITTER: Coker MO 

PROVIDER: S-EPMC9338228 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature