Correlation between apparent diffusion coefficient and tumor-stroma ratio in hybrid ¹⁸F-FDG PET/MRI: preliminary results of a rectal cancer cohort study.

ABSTRACT:

Background

To explore possible correlations between the tumor-stroma ratio (TSR) and different imaging features of fluorine-18-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (¹⁸F-FDG PET/MRI) in untreated rectal cancer patients.

Methods

A patients with rectal cancer were included in this study. All participants were examined preoperatively with whole-body ¹⁸F-FDG PET/MRI. Two pathologists evaluated the TSR of tumors together. Apparent diffusion coefficient (ADC) values and PET-related parameters of the primary lesions were measured and compared between the stroma-high and stroma-low groups. Pearson's correlation or Spearman's rank correlation were used to evaluate the correlation between the ADC values, PET-related parameters

SUBMITTER: Hu S 

PROVIDER: S-EPMC9338373 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature