Quality of dietary fat and risk of Alzheimer's disease and dementia in adults aged ≥50 years: a systematic review.

ABSTRACT:

Objective

To identify, critically appraise, and synthesize evidence on the effect of quality of dietary fat intake and different classes of fatty acids on the risk of Alzheimer's disease (AD) and dementia in adults aged ≥50 years.

Methods

We searched MEDLINE, EMBASE, Cochrane Central of Controlled Trials, and Scopus for clinical trials and prospective cohort studies published until May 2021. Two reviewers independently screened retrieved literature, extracted relevant data, and performed risk of bias assessment. Classes of fatty acids included were saturated fatty acids (SFAs), trans fatty acids (TFAs), monounsaturated fatty acids (MUFAs), poly-unsaturated fatty acids (PUFAs), and their subtypes and sources. Given between-study heterogeneity, we did not perform meta-analyses

SUBMITTER: Nwaru BI 

PROVIDER: S-EPMC9338447 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature