The effect of hydroalcoholic extract of Psidium guajava L. on experimentally induced oral mucosal wound in rat.

ABSTRACT:

Background

The aim of this study was to evaluate the biological effects of hydroalcoholic extract of Psidium guajava L leaves and phenytoin as a standard agent on the induced oral mucosal wound.

Methods

Hundred seventy Sprague Dawley rats were grouped in 5 clusters randomly. Oral mucosal wounds were induced in all rats except for the control group. Phenytoin and guajava leaf extract were used as a mouthwash. Twelve rats from the 5 groups were euthanized on day 7^th and 10^th, and 10 rats from each group were sacrificed on the 14^th day. Interleukin-6 and total antioxidant capacity were determined in the serum. The tissues were evaluated for pathological and stereological assessments. Phytochemical analyses were performed on the hydroalcoholic ex

SUBMITTER: Ghaderi F 

PROVIDER: S-EPMC9338486 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature