Distribution and clinical significance of circulating CD8⁺CD28^- regulatory T cells in the peripheral blood of patients with pulmonary tuberculosis.

ABSTRACT:

Background

Regulatory T cells (Treg cells) in the peripheral blood of patients with pulmonary tuberculosis (PTB) may be closely related to the progression of PTB. In this study, the distribution characteristics and clinical importance of CD8⁺CD28^- Treg cells in patients with tuberculosis were systematically analyzed, and the role and importance of CD8⁺CD28^- Treg cells in influencing the immune response and progression of tuberculosis were discussed, which will provide immunological indices and reference values for the clinical diagnosis of tuberculosis.

Methods

Flow cytometry, sputum smears and computed tomography imaging were used to analyze the distribution characteristics of CD8⁺CD28^- Treg cells in the peri

SUBMITTER: Yu X 

PROVIDER: S-EPMC9338636 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature