Nonsteroidal anti-inflammatory drug exposure and the risk of microscopic colitis.

ABSTRACT:

Background

Medication consumption has been suggested as a risk factor for microscopic colitis (MC), but studies of varying design have yielded inconsistent results. Our aim was to evaluate the association between medications and MC.

Methods

A hybrid cohort of prospectively identified patients undergoing colonoscopy with biopsies for suspicion of MC (N = 144) and patients with MC enrolled within three months of diagnosis into an MC registry (N = 59) were surveyed on medication use. Medication use was compared between patients with and without diagnosis of MC by chi-squared test and binomial logistic regression adjusted for known risk factors of MC: age and gender.

Results

In total, 80 patients with MC (21 new, 59 registry) were enrolled. Patients with MC were more like

SUBMITTER: Yen EF 

PROVIDER: S-EPMC9338644 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature