Glycemic Markers and Heart Failure Subtypes: The Multi-Ethnic Study of Atherosclerosis (MESA).

ABSTRACT:

Background

Although diabetes increases heart failure (HF) risk, it is unclear how various dysglycemia markers (hemoglobin A_1C [HbA_1C], fasting plasma glucose [FPG], homeostasis model assessment of insulin resistance, and fasting insulin) are associated with HF subtypes (HF with preserved ejection fraction [HFpEF] and HF with reduced ejection fraction [HFrEF]). We assessed the relation of markers of dysglycemia and risks of HFpEF and HFrEF.

Methods and results

We included 6688 adults without prevalent cardiovascular disease who attended the first MESA visit (2000-2002) and were followed for incident hospitalized HF (HFpEF or HFrEF). Association of glycemic markers and status (normoglycemia, prediabetes, diabetes) with HFpEF and HFrEF were evaluated using

SUBMITTER: Echouffo-Tcheugui JB 

PROVIDER: S-EPMC9339035 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature