QTLViewer: an interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations.
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ABSTRACT:
SUBMITTER: Vincent M
PROVIDER: S-EPMC9339332 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Publications
QTLViewer: an interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations.
Vincent Matthew M Gerdes Gyuricza Isabela I Keele Gregory R GR Gatti Daniel M DM Keller Mark P MP Broman Karl W KW Churchill Gary A GA
G3 (Bethesda, Md.) 20220701 8
The Collaborative Cross and the Diversity Outbred mouse populations are related multiparental populations, derived from the same 8 isogenic founder strains. They carry >50 M known genetic variants, which makes them ideal tools for mapping genetic loci that regulate phenotypes, including physiological and molecular traits. Mapping quantitative trait loci requires statistical and computational training, which can present a barrier to access for some researchers. The QTLViewer software allows us ...[more]
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