The role of nativity in heterogeneous dementia incidence in a large cohort of three Asian American groups and white older adults in California.

ABSTRACT:

Introduction

Literature shows lower dementia incidence in Asian American groups versus whites, varying by Asian ethnicity. One hypothesized driver is nativity differences (eg, healthy immigrant effect).

Methods

We followed a cohort of 6243 Chinese, 4879 Filipino, 3256 Japanese, and 141,158 white Kaiser Permanente Northern California members for incident dementia (2002 to 2020), estimating age-adjusted dementia incidence rates by ethnicity and nativity, and hazard ratios (HR) for nativity on dementia incidence using ethnicity-stratified age- and sex-adjusted Cox proportional hazards models.

Results

Dementia incidence appeared higher in foreign- versus US-born Filipinos (HR, 95% confidence interval: 1.39, 1.02 to 1.89); differences were small in Japanese (1.07, 0.88 to

SUBMITTER: Hayes-Larson E 

PROVIDER: S-EPMC9339576 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature