Disruption of Functional Brain Networks Underlies the Handwriting Deficit in Children With Developmental Dyslexia.

ABSTRACT: Developmental dyslexia (DD) is a neurological-based learning disorder that affects 5-17.5% of children. Handwriting difficulty is a prevailing symptom of dyslexia, but its neural mechanisms remain elusive. Using functional magnetic resonance imaging (fMRI), this study examined functional brain networks associated with handwriting in a copying task in Chinese children with DD (n = 17) and age-matched children (n = 36). We found that dyslexics showed reduced network connectivity between the sensory-motor network (SMN) and the visual network (VN), and between the default mode network (DMN) and the ventral attention network (VAN) during handwriting, but not during drawing geometric figures. Moreover, the connectivity strength of the networks showing group differences was correlat

SUBMITTER: Liu Z 

PROVIDER: S-EPMC9339653 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature