Symptom severity is associated with leftward lateralization upon contextual modulation of visual vertical in patients with schizophrenia

ABSTRACT:

Background

Contextual processing dysfunction in patients with schizophrenia (SCZ) is not uniform and task-dependent. In SCZ, studies on the rod and frame test (RFT), which evaluates contextual modulation of verticality perception, are sparse. A main study that utilized a two-alternative forced choice design for judging rod verticality reported equivalent strength of RFT contextual modulation in healthy controls and SCZ. The current study aims to uncover any potential differences in contextual modulation between controls and SCZ with an adjustment method on a computerized RFT.

Materials and methods

A total of 17 healthy controls and 15 SCZ aligned an oriented rod to their perceived vertical with a computer mouse under four randomized frame presentations: absent frame, non-

SUBMITTER: Razzak A 

PROVIDER: S-EPMC9339704 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature