Dataset Information

Influence of smoking history on the evolution of hospitalized in COVID-19 positive patients: Results from the SEMI-COVID-19 registry.

ABSTRACT:

Introduction

Smoking can play a key role in SARS-CoV-2 infection and in the course of the disease. Previous studies have conflicting or inconclusive results on the prevalence of smoking and the severity of the coronavirus disease (COVID-19).

Methods

Observational, multicenter, retrospective cohort study of 14,260 patients admitted for COVID-19 in Spanish hospitals between February and September 2020. Their clinical characteristics were recorded and the patients were classified into a smoking group (active or former smokers) or a non-smoking group (never smokers). The patients were followed up to one month after discharge. Differences between groups were analysed. A multivariate logistic regression and Kapplan Meier curves analysed the relationship between smoking and in-hospital mortality.

Results

The median age was 68.6 (55.8-79.1) years, with 57.7% of males. Smoking patients were older (69.9 (59.6-78.0 years)), more frequently male (80.3%) and with higher Charlson index (4 (2-6)) than non-smoking patients. Smoking patients presented a worse evolution, with a higher rate of admission to the intensive care unit (ICU) (10.4 vs. 8.1%), higher in-hospital mortality (22.5 vs. 16.4%) and readmission at one month (5.8 vs. 4.0%) than in non-smoking patients. After multivariate analysis, smoking remained associated with these events.

Conclusions

Active or past smoking is an independent predictor of poor prognosis in patients with COVID-19. It is associated with higher ICU admissions and in-hospital mortality.

SUBMITTER: Navas Alcantara MS

PROVIDER: S-EPMC9339973 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Publications

Influence of smoking history on the evolution of hospitalized in COVID-19 positive patients: Results from the SEMI-COVID-19 registry.

Navas Alcántara María Sierra MS Montero Rivas Lorena L Guisado Espartero María Esther ME Rubio-Rivas Manuel M Ayuso García Blanca B Moreno Martinez Francisco F Ausín García Cristina C Taboada Martínez María Luisa ML Arnalich Fernández Francisco F Martínez Murgui Raúl R Molinos Castro Sonia S Ramos Muñoz Maria Esther ME Fernández-Garcés Mar M Carreño Hernandez Mari Cruz MC García García Gema María GM Vázquez Piqueras Nuria N Abadía-Otero Jesica J Lajara Villar Lourdes L Salazar Monteiro Cristina C Pascual Pérez María de Los Reyes MLR Perez-Martin Santiago S Collado-Aliaga Javier J Antón-Santos Juan-Miguel JM Lumbreras-Bermejo Carlos C

Medicina clinica (English ed.) 20220801 5

<h4>Introduction</h4>Smoking can play a key role in SARS-CoV-2 infection and in the course of the disease. Previous studies have conflicting or inconclusive results on the prevalence of smoking and the severity of the coronavirus disease (COVID-19).<h4>Methods</h4>Observational, multicenter, retrospective cohort study of 14,260 patients admitted for COVID-19 in Spanish hospitals between February and September 2020. Their clinical characteristics were recorded and the patients were classified int ...[more]

PMID: 35935808

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Dataset Information

Influence of smoking history on the evolution of hospitalized in COVID-19 positive patients: Results from the SEMI-COVID-19 registry.

Introduction

Methods

Results

Conclusions

Publications

Influence of smoking history on the evolution of hospitalized in COVID-19 positive patients: Results from the SEMI-COVID-19 registry.

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