Features of antibody responses after SARS-COV-2 infection in healthcare workers in the first wave of COVID-19 pandemic in Mexico City.

ABSTRACT:

Objective

To investigate the antibody response to SARS-CoV-2 and identify associated factors in frontline and second-line healthcare workers (HCWs) at a large hospital in Mexico City during the first wave of COVID-19 pandemic.

Methods

This was a cross-sectional study of HCWs returning to work following mandatory isolation after recovering from COVID-19. Immunoglobulin (Ig) M and IgG antibodies elicited by SARS-CoV-2 were semiquantitatively measured using densitometric analysis of band intensities in lateral flow assay (LFA) devices. The mean pixel intensity (dots-per-inch [dpi]) of each band on the LFA was considered a measure of antibody titre.

Results

Of the 111 HCWs involved in the study, antibody responses were detected in 73/111 (66%) participants. Severe COVID s

SUBMITTER: Thompson-Bonilla MDR 

PROVIDER: S-EPMC9340344 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature