Higher order visual areas enhance stimulus responsiveness in mouse primary visual cortex.

ABSTRACT: Over the past few years, the various areas that surround the primary visual cortex (V1) in the mouse have been associated with many functions, ranging from higher order visual processing to decision-making. Recently, some studies have shown that higher order visual areas influence the activity of the primary visual cortex, refining its processing capabilities. Here, we studied how in vivo optogenetic inactivation of two higher order visual areas with different functional properties affects responses evoked by moving bars in the primary visual cortex. In contrast with the prevailing view, our results demonstrate that distinct higher order visual areas similarly modulate early visual processing. In particular, these areas enhance stimulus responsiveness in the primary visual cortex, by more

SUBMITTER: Oude Lohuis MN 

PROVIDER: S-EPMC9340391 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature