Functional connectivity for the language network in the developing brain: 30 weeks of gestation to 30 months of age.

ABSTRACT: Although the neural scaffolding for language is putatively present before birth, the maturation of functional connections among the key nodes of the language network, Broca's and Wernicke's areas, is less known. We leveraged longitudinal and cross-sectional data from three sites collected through six studies to track the development of functional circuits between Broca's and Wernicke's areas from 30 weeks of gestation through 30 months of age in 127 unique participants. Using resting-state fMRI data, functional connectivity was calculated as the correlation between fMRI time courses from pairs of regions, defined as Broca's and Wernicke's in both hemispheres. The primary analysis evaluated 23 individuals longitudinally imaged from 30 weeks postmenstrual age (fetal) through the first postna

SUBMITTER: Scheinost D 

PROVIDER: S-EPMC9340393 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature