Association of COPD exacerbations and acute cardiovascular events: a systematic review and meta-analysis.

ABSTRACT:

Background

The majority of patients with chronic obstructive pulmonary disease (COPD) suffer from comorbid cardiovascular (CV) disease. Accumulating evidence suggests a temporal association between COPD exacerbations and acute CV events, possibly due to lung hyperinflation, increased hypoxemia and systemic inflammation. The aims of the study were to estimate the risk of (1) acute CV events [acute myocardial infarction (AMI), CV-related death] or stroke in the months following a COPD exacerbation and (2) COPD exacerbation in the months following an acute CV event.

Methods

A systematic literature review of observational studies published since 2000 was conducted by searching literature databases (Medline and Embase). Studies were eligible if conducted in adults with COPD, expo

SUBMITTER: Mullerova H 

PROVIDER: S-EPMC9340406 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature