Serological evidence of possible high levels of undetected transmission of Zika virus among Papua New Guinea military personnel, 2019.

ABSTRACT:

Objectives

The Papua New Guinea (PNG) Health Department retrospectively reported six cases of Zika virus (ZIKV) from a cohort of febrile patients during outbreaks of dengue and malaria in 2016. However, the transmission of ZIKV remains unclear due to lack of testing capability. This study aimed to determine the level of immunity to ZIKV among PNG military personnel (PNGMP) in 2019.

Methods

Sera of 208 PNGMP recruited in April 2019 was tested for the presence of anti-ZIKV immunoglobulin G (IgG) and M (IgM) antibodies using Euroimmun IgG/IgM detection kits, and anti-ZIKV neutralizing antibody (Nab) against a ZIKV African strain on all anti-ZIKV-IgG/IgM⁺ samples.

Results

Anti-ZIKV seropositivity of these sera was as follows: IgG, 67%; IgM, 9%; and Nab, 65%. Fi

SUBMITTER: Grant R 

PROVIDER: S-EPMC9340500 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature