Point-of-care sural nerve conduction could predict the presence of cardiovascular autonomic neuropathy in type 1 diabetes mellitus.

ABSTRACT:

Aims

Assessment for cardiovascular autonomic neuropathy (CAN) in patients with type 1 diabetes mellitus remains time-consuming in the clinical setting. We aimed to examine the diagnostic performance of a portable point-of-care diagnostic tool (POCD) for assessing sural nerve conduction during the screening of CAN.

Methods

Nerve amplitude (AMP_POCD ) and conduction velocity (CV_POCD ) were measured in a cross-sectional study including 198 asymptomatic patients with type 1 diabetes. CAN was diagnosed by the Ewing score and power spectral heart rate [low-frequency (LF) and high-frequency (HF) activity]. Diagnostic accuracy was determined by ROC curves.

Results

CV_POCD and AMP_POCD showed positive correlations with LF and HF, and a

SUBMITTER: Nattero-Chavez L 

PROVIDER: S-EPMC9340859 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature