Obstructive sleep apnea, prediabetes and progression of type 2 diabetes: A systematic review and meta-analysis.

ABSTRACT:

Aims/introduction

Obstructive sleep apnea (OSA) is related to prediabetes and diabetes. Whether patients with OSA have a higher risk of prediabetes/diabetes remains unclear. We aimed to carry out a meta-analysis of published studies to evaluate the relationships between OSA and prediabetes and diabetes, and the impact of the severity of OSA on diabetes.

Materials and methods

The PubMed, EMBASE and Cochrane databases were searched from January 2011 to July 2021. The associations between OSA and impaired fasting glucose, impaired glucose tolerance, impaired glucose regulation and diabetes mellitus were analyzed. We estimated the pooled odds ratios using fixed or random effects models. We included 25 studies comprising a total of 154,948 patients with OSA and risk factors for p

SUBMITTER: Wang C 

PROVIDER: S-EPMC9340883 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature