Change in individual chronic obstructive pulmonary disease assessment test item scores after short-term bronchodilator therapy and its impact on exacerbation in treatment-naive patients with chronic obstructive pulmonary disease.

ABSTRACT:

Background

The chronic obstructive pulmonary disease (COPD) assessment test (CAT) measures the health status of patients with COPD. We aimed to investigate the change in individual CAT scores after short-term bronchodilator therapy among treatment-naïve patients with COPD.

Methods

Data from 148 patients newly diagnosed with COPD between January 2016 and April 2020 were retrospectively analyzed. We compared the CAT score, modified Medical Research Council (mMRC) dyspnea grade, and forced expiratory volume in 1 s (FEV₁) before and after short-term (6 ± 2 months) bronchodilator therapy. We analyzed the change trends using generalized estimating equations.

Results

The mean patient age was 70.9 years, and 92.6% were male. The total CAT score did not significantl

SUBMITTER: Kim BG 

PROVIDER: S-EPMC9340891 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature