Correcting magnification error in foveal avascular zone area measurements of optical coherence tomography angiography images with estimated axial length.

ABSTRACT:

Background

To generate and validate a method to estimate axial length estimated (AL_est) from spherical equivalent (SE) and corneal curvature [keratometry (K)], and to determine if this AL_est can replace actual axial length (AL_act) for correcting transverse magnification error in optical coherence tomography angiography (OCTA) images using the Littmann-Bennett formula.

Methods

Data from 1301 participants of the Raine Study Gen2-20 year follow-up were divided into two datasets to generate (n = 650) and validate (n = 651) a relationship between AL, SE, and K. The developed formula was then applied to a separate dataset of 46 participants with AL, SE, and K measurements and OCTA images to estimate and compare the performance of AL_est a

SUBMITTER: Dutt DDCS 

PROVIDER: S-EPMC9341098 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature