Characterization of compliance phenotypes in COVID-19 acute respiratory distress syndrome.

ABSTRACT:

Background

Coronavirus disease 2019-associated acute respiratory distress syndrome (COVID-19 ARDS) seems to differ from the "classic ARDS", showing initial significant hypoxemia in the face of relatively preserved compliance and evolving later in a scenario of poorly compliant lungs. We tested the hypothesis that in patients with COVID-19 ARDS, the initial value of static compliance of respiratory system (Crs) (1) depends on the previous duration of the disease (i.e., the fewer days of illness, the higher the Crs and vice versa) and (2) identifies different lung patterns of time evolution and response to prone positioning.

Methods

This was a single-center prospective observational study. We enrolled consecutive mechanically ventilated patients with a diagnosis of COVID-19 wh

SUBMITTER: Zacchetti L 

PROVIDER: S-EPMC9341412 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature