Advances in S gene targeted genome-editing and its applicability to disease resistance breeding in selected Solanaceae crop plants.

ABSTRACT: Genome-editing tools for the development of traits to tolerate abiotic and biotic adversaries are the recently devised breeding techniques revolutionizing molecular breeding by addressing the issues of rapidness and precision. To that end, disease resistance development by disrupting disease susceptibility genes (S genes) to intervene in the biological mechanism of pathogenicity has significantly improved the techniques of molecular breeding. Despite the achievements in genome-editing aimed at the intervention of the function of susceptibility determinants or gene regulatory elements, off-target effects associated with yield-related traits are still the main setbacks. The challenges are attributed to the complexity of the inheritance of traits controlled by pleiotropic genes. Therefore, a

SUBMITTER: Barka GD 

PROVIDER: S-EPMC9342254 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature