Effect of inotropic agents on oxygenation and cerebral perfusion in acute brain injury.

ABSTRACT:

Introduction

Tissue hypoxia and insufficient energy delivery is one of the mechanisms behind the occurrence of several complications in acute brain injured patients. Several interventions can improve cerebral oxygenation; however, the effects of inotropic agents remain poorly characterized.

Methods

Retrospective analysis including patients suffering from acute brain injury and monitored with brain oxygen pressure (PbtO₂) catheter, in whom inotropic agents were administered according to the decision of the treating physician's decision; PbtO₂ values were collected before, 1 and 2 h after the initiation of therapy from the patient data monitoring system. PbtO₂ "responders" were patients with a relative increase in PbtO₂ from baseline

SUBMITTER: Coppalini G 

PROVIDER: S-EPMC9343780 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature