Phenotype of Asthma-COPD Overlap in COPD and Severe Asthma Cohorts.

ABSTRACT:

Background

Asthma and chronic obstructive pulmonary disease (COPD) are airway diseases with similar clinical manifestations, despite differences in pathophysiology. Asthma-COPD overlap (ACO) is a condition characterized by overlapping clinical features of both diseases. There have been few reports regarding the prevalence of ACO in COPD and severe asthma cohorts. ACO is heterogeneous; patients can be classified on the basis of phenotype differences. This study was performed to analyze the prevalence of ACO in COPD and severe asthma cohorts. In addition, this study compared baseline characteristics among ACO patients according to phenotype.

Methods

Patients with COPD were prospectively enrolled into the Korean COPD subgroup study (KOCOSS) cohort. Patients with severe asthma w

SUBMITTER: Joo H 

PROVIDER: S-EPMC9344038 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature