Dataset Information

Distinct neural responses of morningness and eveningness chronotype to homeostatic sleep pressure revealed by resting-state functional magnetic resonance imaging.

ABSTRACT:

Background

Chronotype is an appropriate variable to investigate sleep homeostatic and circadian rhythm. Based on functional MRI, the resting-state functional connectivity (rsFC) of insula-angular decrease with the increase in homeostatic sleep pressure (HSP). However, the distinct neural response of different chronotype remained to be clarified. Therefore, we investigated how HSP influenced insular-angular neural interaction of different chronotype.

Methods

64 morningness-chronotype (MCPs) and 128 eveningness-chronotype participants (ECPs) received resting-state functional MRI (rsfMRI) scan. HSP was divided into three levels (Low, Medium, and High) based on the elapsed time awake. Insular-angular rsFC was calculated for MCPs and ECPs on each HSP.

Results

As the levels of HSP increased, the negative rsFC between right insular and bilateral angular increased in MCPs while decreased in ECPs. Specifically, ECPs compared with MCPs showed lower rsFC at medium levels of HSP, but higher rsFC at high levels of HSP. In addition, ECPs compared with MCPs exhibited lower rsFC between right insular and right angular at low levels of HSP.

Conclusion

The distinct modes of rsFC was found in different chronotype in response to HSP. The results provided the foundation and evidence for investigating the processes of circadian rhythm and sleep homeostatic.

SUBMITTER: Wang H

PROVIDER: S-EPMC9344083 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Publications

Distinct neural responses of morningness and eveningness chronotype to homeostatic sleep pressure revealed by resting-state functional magnetic resonance imaging.

Wang Haien H Tian Yun Y Wang Yulin Y He Qinghua Q Qiu Jiang J Feng Tingyong T Chen Hong H Lei Xu X

CNS neuroscience & therapeutics 20220614 9

<h4>Background</h4>Chronotype is an appropriate variable to investigate sleep homeostatic and circadian rhythm. Based on functional MRI, the resting-state functional connectivity (rsFC) of insula-angular decrease with the increase in homeostatic sleep pressure (HSP). However, the distinct neural response of different chronotype remained to be clarified. Therefore, we investigated how HSP influenced insular-angular neural interaction of different chronotype.<h4>Methods</h4>64 morningness-chronoty ...[more]

PMID: 35699408

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Dataset Information

Distinct neural responses of morningness and eveningness chronotype to homeostatic sleep pressure revealed by resting-state functional magnetic resonance imaging.

Background

Methods

Results

Conclusion

Publications

Distinct neural responses of morningness and eveningness chronotype to homeostatic sleep pressure revealed by resting-state functional magnetic resonance imaging.

Similar Datasets

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