Distinct neural responses of morningness and eveningness chronotype to homeostatic sleep pressure revealed by resting-state functional magnetic resonance imaging.

ABSTRACT:

Background

Chronotype is an appropriate variable to investigate sleep homeostatic and circadian rhythm. Based on functional MRI, the resting-state functional connectivity (rsFC) of insula-angular decrease with the increase in homeostatic sleep pressure (HSP). However, the distinct neural response of different chronotype remained to be clarified. Therefore, we investigated how HSP influenced insular-angular neural interaction of different chronotype.

Methods

64 morningness-chronotype (MCPs) and 128 eveningness-chronotype participants (ECPs) received resting-state functional MRI (rsfMRI) scan. HSP was divided into three levels (Low, Medium, and High) based on the elapsed time awake. Insular-angular rsFC was calculated for MCPs and ECPs on each HSP.

Results

As the levels

SUBMITTER: Wang H 

PROVIDER: S-EPMC9344083 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature