Foveal Curvature and Its Associations in UK Biobank Participants.

ABSTRACT:

Purpose

To examine whether sociodemographic, and ocular factors relate to optical coherence tomography (OCT)-derived foveal curvature (FC) in healthy individuals.

Methods

We developed a deep learning model to quantify OCT-derived FC from 63,939 participants (age range, 39-70 years). Associations of FC with sociodemographic, and ocular factors were obtained using multilevel regression analysis (to allow for right and left eyes) adjusting for age, sex, ethnicity, height (model 1), visual acuity, spherical equivalent, corneal astigmatism, center point retinal thickness (CPRT), intraocular pressure (model 2), deprivation (Townsend index), higher education, annual income, and birth order (model 3). Fovea curvature was modeled as a z-score.

Results

Males had on average stee

SUBMITTER: Olvera-Barrios A 

PROVIDER: S-EPMC9344217 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature