Synthesis and bioimaging of a BODIPY-based fluorescence quenching probe for Fe³.

ABSTRACT: Iron is the main substance for maintaining life. Real-time determination of ferric ion (Fe³⁺) in living cells is of great significance for understanding the relationship of Fe³⁺ concentration changes with various physiological and pathological processes. Fluorescent probes are suitable for the detection of trace metal ions in cells due to their low toxicity and high sensitivity. In this work, a boron-dipyrromethene-based fluorescent probe (BODIPY-CL) for selective detection of Fe³⁺ was synthesized. The fluorescence emission of BODIPY-CL was determined at 516 nm. In a pH range of 1 to 10, the probe BODIPY-CL exhibits a quenching response to Fe³⁺. Meanwhile, BODIPY-CL showed a highly selective response to Fe³⁺ compared with 16 kinds of m

SUBMITTER: Leng J 

PROVIDER: S-EPMC9344281 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature