Datasets for a simulated family-based exome-sequencing study.

ABSTRACT: We present simulated exome-sequencing data for 150 families from a North American admixed population, ascertained to contain at least four members affected with lymphoid cancer. These data include information on the ascertained families as well as single-nucleotide variants on the exome of affected family members. We provide a brief overview of the simulation steps and links to the associated software scripts. The resulting data are useful to identify genomic patterns and disease inheritance in families with multiple disease-affected members.

SUBMITTER: Epasinghege Dona N 

PROVIDER: S-EPMC9344320 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature