Efficacy of low-dose corticosteroids in patients with acute respiratory distress syndrome: a prospective observational study.

ABSTRACT:

Background

There is still no agreement on whether corticosteroids can reduce mortality in patients with acute respiratory distress syndrome (ARDS). The aim of this study was to investigate the efficacy of low-dose corticosteroid administration in patients with ARDS.

Methods

A prospective observational study of patients with ARDS in 17 hospitals in China was performed between March 2016 and February 2018. Propensity score matching was performed to adjust for differences in baseline characteristics between different groups. The effects of corticosteroids were assessed by using the Kaplan-Meier method and a multivariate Cox regression.

Results

A total of 527 ARDS patients were enrolled in the study. Sixty-five patients (12.3%) were administered low-dose (methylprednisolo

SUBMITTER: Zhang R 

PROVIDER: S-EPMC9344422 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature