The association between common serum adipokines levels and postmenopausal osteoporosis: A meta-analysis.

ABSTRACT: The clinical relevance of blood levels of adipokines in individuals with postmenopausal osteoporosis (PMOP) has not been previously clarified. We performed this meta-analysis to clarify the association between three common adipokines levels and the occurrence of PMOP. PubMed, Embase, Cochrane library, and China National Knowledgement Infrastructure (CNKI) were searched for collecting articles published before 31 October 2021, without language and status restrictions. Fourteen studies met the selection criteria. Meta-analysis revealed that blood leptin level was remarkably lower (mean difference [MD], -1.94; 95% confidence interval [CI], -3.83 to -0.06; I²  = 96%) and adiponectin level was remarkably higher (MD, 3.48; 95% CI, 2.36 to 4.60; I²  = 90%) in individuals wit

SUBMITTER: Shu L 

PROVIDER: S-EPMC9344814 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature