Temporal Dynamics of Event-Related Potentials during Inhibitory Control Characterize Age-Related Neural Compensation

ABSTRACT: Aging is accompanied by frontal lobe and non-dominant hemisphere recruitment that supports executive functioning, such as inhibitory control, which is crucial to all cognitive functions. However, the spatio-temporal sequence of processing underlying successful inhibition and how it changes with age is understudied. Thus, we capitalized on the temporal precision of event-related potentials (ERPs) to assess the functional lateralization of N200 (conflict monitoring) and P300 (inhibitory performance evaluation) in young and healthy older adults during comparably performed successful stop-signal inhibition. We additionally used temporal principal components analysis (PCA) to further interrogate the continuous spatio-temporal dynamics underlying N200 and P300 activation for each group. Young ad

SUBMITTER: Paitel E 

PROVIDER: S-EPMC9345327 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature