Effect of time-dependent ibuprofen administration on the post operatory after impacted third molar extraction: a cross-over randomized controlled trial.

ABSTRACT:

Purpose

To evaluate time-dependent administration of ibuprofen in a lower third molar extraction model.

Methods

Eleven patients requiring bilateral surgical removal of lower third molars were recruited and randomized into a blinded crossover randomized controlled trial. For 3 days after surgery, the control group was prescribed ibuprofen 400 mg every 8 h. On the other hand, the experimental group received also ibuprofen 400 mg at breakfast and lunch, replacing the dinner intake with a placebo. Pain measurements (Visual Analog Scale from 0 to 10) were recorded at baseline, 24, 48, and 72 h postoperatively. Facial swelling and trismus were also measured at baseline, 24, and 72 h postoperatively.

Results

Postoperative swelling and pain perception did not show significati

SUBMITTER: Perez-Gonzalez F 

PROVIDER: S-EPMC9345738 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature