A patient-reported outcome measure for patients with pituitary adenoma undergoing transsphenoidal surgery.

ABSTRACT:

Purpose

Pituitary adenomas affect patients' quality-of-life (QoL) across several domains, with long-term implications even following gross-total resection or disease remission. While clinical outcomes can assess treatment efficacy, they do not capture variations in QoL. We present the development and validation of a patient reported outcome measure (PROM) for patients with pituitary adenomas undergoing transsphenoidal surgery.

Methods

The COSMIN checklist informed the development of the pituitary outcome score (POS). Consecutive patients undergoing surgical treatment for suspected pituitary adenoma at a single centre were included prospectively. An expert focus group and patient interviews informed item generation. Item reduction was conducted through exploratory factor anal

SUBMITTER: Karvandi E 

PROVIDER: S-EPMC9345822 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature