Effect of temporal sampling protocols on myocardial blood flow measurements using Rubidium-82 PET.

ABSTRACT:

Background

A variety of temporal sampling protocols is used worldwide to measure myocardial blood flow (MBF). Both the length and number of time frames in these protocols may alter MBF and myocardial flow reserve (MFR) measurements. We aimed to assess the effect of different clinically used temporal sampling protocols on MBF and MFR quantification in Rubidium-82 (Rb-82) PET imaging.

Methods

We retrospectively included 20 patients referred for myocardial perfusion imaging using Rb-82 PET. A literature search was performed to identify appropriate sampling protocols. PET data were reconstructed using 14 selected temporal sampling protocols with time frames of 5-10 seconds in the first-pass phase and 30-120 seconds in the tissue phase. Rest and stress MBF and MFR were calculated

SUBMITTER: Koenders SS 

PROVIDER: S-EPMC9345838 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature