Assessment of a digital and an analog PET/CT system for accurate myocardial perfusion imaging with a flow phantom.

ABSTRACT: In Myocardial Perfusion Imaging (MPI) with Positron Emission Tomography/Computed Tomography (PET/CT) systems, accurate quantification is essential. We assessed flow quantification accuracy over various injected activities using a flow phantom.

Methods

The study was performed on the digital 4-ring Discovery MI (DMI-20) and analog Discovery 690 (D690) PET/CT systems, using 325-1257 MBq of [¹⁵O]H₂O. PET performance and flow quantification accuracy were assessed in terms of count-rates, dead-time factors (DTF), scatter fractions (SF), time-activity curves (TACs), areas-under-the-curves (AUCs) and flow values.

Results

On DMI-20, prompts of 12.8 Mcps, DTF of 2.06 and SF of 46.1% were measured with 1257 MBq of activity. On the D690, prompts of 6.85 Mcps, DTF of

SUBMITTER: Siekkinen R 

PROVIDER: S-EPMC9345842 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature