Scope of repurposed drugs against the potential targets of the latest variants of SARS-CoV-2.

ABSTRACT: The unprecedented outbreak of the severe acute respiratory syndrome (SARS) Coronavirus-2, across the globe, triggered a worldwide uproar in the search for immediate treatment strategies. With no specific drug and not much data available, alternative approaches such as drug repurposing came to the limelight. To date, extensive research on the repositioning of drugs has led to the identification of numerous drugs against various important protein targets of the coronavirus strains, with hopes of the drugs working against the major variants of concerns (alpha, beta, gamma, delta, omicron) of the virus. Advancements in computational sciences have led to improved scope of repurposing via techniques such as structure-based approaches including molecular docking, molecular dynamic simulations and

SUBMITTER: Niranjan V 

PROVIDER: S-EPMC9346052 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature