Non-thyroidal second primary malignancy in papillary thyroid cancer patients.

ABSTRACT:

Introduction

The occurrence of non-thyroidal second primary malignancy (NTSPM) in patients with papillary thyroid cancer (PTC) is well documented, but epidemiological data are conflicting.

Objective

The aim of this study was to evaluate the incidence of NTSPM in a large series of patients with PTC and to assess its potential risk factors.

Methods

Single-center cohort study with retrospective data collection conducted on consecutive PTC patients diagnosed from 1988 to 2018 with a minimum follow-up time of 2 years. NTSPM was defined as any primary malignancy with histological confirmation occurring in an anatomical site other than the thyroid. According to the timing of occurrence, NTSPM were subdivided into anachronous, synchronous or metachronous (diagnosed >6 months

SUBMITTER: Borges Duarte D 

PROVIDER: S-EPMC9346322 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature