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Parathyroidectomy versus cinacalcet in the treatment of tertiary hyperparathyroidism after kidney transplantation: a retrospective study.


ABSTRACT:

Background

Hyperparathyroidism is common in patients with chronic kidney disease with reduced renal function and has been observed after kidney transplantation. The optimal treatment for cases in which hyperparathyroidism persists after kidney transplantation has not been determined.

Methods

This retrospective study included 83 patients with tertiary hyperparathyroidism who underwent kidney transplantation between 2000 and 2018 at a single tertiary center in Korea. Sixty-four patients underwent parathyroidectomy and 19 patients were treated with cinacalcet following renal transplantation. Biochemical parameters and clinical outcomes were compared between the two groups.

Results

Serum calcium and parathyroid hormone (PTH) levels improved in both the parathyroidectomy a

SUBMITTER: Jung S 

PROVIDER: S-EPMC9346402 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature