Small airway dysfunction in Chinese patients with idiopathic pulmonary fibrosis.

ABSTRACT:

Background

Recent years, idiopathic pulmonary fibrosis (IPF) is thought to be a disease of alveoli as well as small airways. This study aimed to demonstrate the clinical feature, predictor, and prognosis of small airway dysfunction (SAD) in Chinese patients with IPF.

Methods

We enrolled 416 patients with IPF who hospitalized in Beijing Chao-Yang Hospital from 2000 to 2014 in this study, and the follow-up ended at December 2016. We collected demographic information, clinical examination results, spirometry results, HRCT results, and blood gas results during the study. Logistic regression analysis was used to identify the predictor for SAD. The COX proportional hazard model was used to analysis the prognosis effect of SAD.

Results

Among all the participants, 165 (39.66%

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9347131 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature