Impact of solid organ transplant status on outcomes of hospitalized patients with COVID-19 infection.

ABSTRACT:

Background

The COVID-19 pandemic has caused significant morbidity and mortality in solid organ transplant (SOT) recipients. However, it remains unclear whether the risk factor for SOT patients is the immunosuppression inherent to transplantation versus patient comorbidities.

Methods

We reviewed outcomes in a cohort of SOT (n = 129) and non-SOT (NSOT) patients (n = 708) admitted to the University of California, Los Angeles for COVID-19 infection. Data analyses utilized multivariate logistic regression to evaluate the impact of patient demographics, comorbidities, and transplant status on outcomes. SOT patients were analyzed by kidney SOT (KSOT) versus nonkidney SOT (NKSOT) groups.

Results

SOT and NSOT patients with COVID-19 infection differed in terms of patient age, e

SUBMITTER: Schaenman J 

PROVIDER: S-EPMC9347588 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature