Dataset Information

Epidemiological and clinical characteristics of pregnant women and neonates with COVID-19 in Northwest Mexico.

ABSTRACT:

Introduction

The SARS-CoV-2 virus, which causes COVID-19, has spread quickly worldwide, causing millions of cases and thousands of deaths. Some risk factors in the general population are related to the development of severe COVID-19 or death, but in pregnant women and neonates, the information is limited.

Objective

To determine the epidemiological and clinical characteristics of pregnant women and neonates diagnosed with COVID-19 by RT-PCR and serological tests, and analyze the relationship between the influenza vaccination and COVID-19 symptoms in infected pregnant women in Sinaloa state.

Methods

We collected samples from 116 pregnant women and 84 neonates from the Women´s Hospital of Sinaloa. They were diagnosed with COVID-19 by RT-PCR and serological tests (IgG), and sociodemographic, clinical and laboratory parameters were recorded.

Results

A total of 11.2% (13/116) of the pregnant women were RT-PCR+, 25% (29/116) were IgG+ and 4.3% (5/116) were positive for both tests. Symptoms such as rhinorrhea (P = .04), cough (P = .02) and polypnea (P = .04) in pregnant women were related to COVID-19, also leukocyte index was higher in pregnant women with COVID-19 (P = .03), but the associations were lost after the Bonferroni correction. No laboratory parameters or underlying diseases were associated with COVID-19, and most infected pregnant women had mild cases. We found an association between the influenza vaccine and less common COVID-19 symptoms in pregnant women who were infected (P = .01). A total of 7.2% (6/84) of neonates were RT-PCR+, 35.7% (30/84) were IgG+, and there were no symptoms or underlying diseases associated with neonates who were infected. In conclusion, this work demonstrated that some symptoms were related to COVID-19, most pregnant women and neonates had mild cases, and the influenza vaccine could decrease the severity of COVID-19 cases in pregnant women.

SUBMITTER: Leon-Sicairos N

PROVIDER: S-EPMC9348056 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Publications

Epidemiological and clinical characteristics of pregnant women and neonates with COVID-19 in Northwest Mexico.

Leon-Sicairos Nidia N Angulo-Zamudio Uriel A UA Pacheco-Avila Mireya M Medina-Ramirez Ivan I Velazquez-Roman Jorge J Angulo-Rocha Jorge J Martínez-Villa Francisco A FA Flores-Villaseñor Hector H Martinez-Garcia Jesus J JJ Sanchez-Cuen Jaime J Garzon-Lopez Oscar O Guel-Gomez Martha M Cuen-Diaz Hector Melesio HM Barajas-Olivas Mario Francisco MF Campos-Romero Abraham A Alcántar-Fernández Jonathan J Esparza Marco A Luna-Ruiz MAL Canizalez-Roman Adrian A

American journal of reproductive immunology (New York, N.Y. : 1989) 20220610 3

<h4>Introduction</h4>The SARS-CoV-2 virus, which causes COVID-19, has spread quickly worldwide, causing millions of cases and thousands of deaths. Some risk factors in the general population are related to the development of severe COVID-19 or death, but in pregnant women and neonates, the information is limited.<h4>Objective</h4>To determine the epidemiological and clinical characteristics of pregnant women and neonates diagnosed with COVID-19 by RT-PCR and serological tests, and analyze the re ...[more]

PMID: 35661465

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Dataset Information

Epidemiological and clinical characteristics of pregnant women and neonates with COVID-19 in Northwest Mexico.

Introduction

Objective

Methods

Results

Publications

Epidemiological and clinical characteristics of pregnant women and neonates with COVID-19 in Northwest Mexico.

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