Electrical Impedance Analysis for Lung Cancer: A Prospective, Multicenter, Blind Validation Study.

ABSTRACT:

Hypothesis

Patients with cancer have different impedances or conductances than patients with benign normal tissue; thus, we can apply electrical impedance analysis (EIA) to identify patients with cancer.

Method

To evaluate EIA's efficacy and safety profile in diagnosing pulmonary lesions, we conducted a prospective, multicenter study among patients with pulmonary lesions recruited from 4 clinical centers (Zhongshan Hospital Ethics Committee, Approval No. 2015-16R and 2017-035(3). They underwent EIA to obtain an Algorithm Composite Score or 'Prolung Index,' PI. The classification threshold of 29 was first tested in an analytical validation set of 144 patients and independently validated in a clinical validation set of 418 patients. The subject's final diagnosis depended on hi

SUBMITTER: Yang D 

PROVIDER: S-EPMC9348894 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature