Bioavailability of phosphorus and kidney function in the Jackson Heart Study.

ABSTRACT:

Background

High phosphorus (P) exposure may have negative effects on kidney function. Nutrient databases provide total P, but bioavailability varies by source.

Objectives

We aimed to assess natural, added, and bioavailable P intake, and to relate these to estimated glomerular filtration rate (eGFR) in the Jackson Heart Study (JHS).

Methods

A total of 3962 African-American participants of the JHS, aged 21-84 y, with urine albumin:creatinine ratio < 30 mg/g, and eGFR ≥ 60 mL · min-1 · 1.73 m-2, and without self-reported kidney disease, were included. Diet was assessed by FFQ. We assigned P in foods as naturally occurring or added, and weighted intake by P bioavailability, based on published literature. Relations between P variables and eGFR were assessed using multivari

SUBMITTER: Duong CN 

PROVIDER: S-EPMC9348986 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature