Early pregnancy vitamin D status is associated with blood pressure in children: an Odense Child Cohort study.

ABSTRACT:

Background

Blood pressure in childhood tracks into later life. Vitamin D status in adults is associated with blood pressure, but the impact of vitamin D status in pregnancy and childhood on blood pressure still needs investigation.

Objective

We investigated whether fetal rather than current vitamin D status is associated with blood pressure in children.

Methods

In a prospective observational study within the population-based Odense Child Cohort (OCC), we examined serum 25-hydroxyvitamin D2+3 [s-25(OH)D] in early and late pregnancy, cord blood, and at 5 y age, and the associations with systolic and diastolic blood pressure (SBP/DBP) in the 5-y-old children (n = 1,677). Multiple regression models were adjusted for maternal country of origin, parity, smoking during pregn

SUBMITTER: Pedersen JN 

PROVIDER: S-EPMC9348989 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature