Dataset Information

Tenosynovial giant cell tumours of the upper and lower cervical spine: two case reports.

ABSTRACT:

Introduction

Tenosynovial giant cell tumours (TSGCTs) usually arise from the synovial membranes of tendon sheaths, bursa, and joints. They are rarely found in the spine. Lesions of the upper cervical spine (C1/2) are extremely rare, with only 13 previous cases reported in the literature. Of these, all previous anterior upper cervical cases (C1/2) have been deemed unresectable and have been managed with immunotherapy or radiological surveillance.

Case presentation

We report two cases of TSGCST in the cervical spine: one with a lesion at C1/2 and another at C6/7.

Discussion

The location of our C1/2 lesion was unique, allowing for a new endoscopic endonasal tissue biopsy method and a new transoral surgical approach for successful gross total resection. Our C6/7 lesion had a more typical location and was removed via a C6/7 laminectomy.

SUBMITTER: Zhu N

PROVIDER: S-EPMC9349175 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

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Publications

Tenosynovial giant cell tumours of the upper and lower cervical spine: two case reports.

Zhu Ning N Campbell Robert R Sadasivan Ananthababu Pattavilakom AP

Spinal cord series and cases 20220803 1

<h4>Introduction</h4>Tenosynovial giant cell tumours (TSGCTs) usually arise from the synovial membranes of tendon sheaths, bursa, and joints. They are rarely found in the spine. Lesions of the upper cervical spine (C1/2) are extremely rare, with only 13 previous cases reported in the literature. Of these, all previous anterior upper cervical cases (C1/2) have been deemed unresectable and have been managed with immunotherapy or radiological surveillance.<h4>Case presentation</h4>We report two cas ...[more]

PMID: 35922405

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Project description:Study designGlobal cross-sectional survey.ObjectiveTo determine the classification accuracy, interobserver reliability, and intraobserver reproducibility of the AO Spine Upper Cervical Injury Classification System based on an international group of AO Spine members.Summary of background dataPrevious upper cervical spine injury classifications have primarily been descriptive without incorporating a hierarchical injury progression within the classification system. Further, upper cervical spine injury classifications have focused on distinct anatomical segments within the upper cervical spine. The AO Spine Upper Cervical Injury Classification System incorporates all injuries of the upper cervical spine into a single classification system focused on a hierarchical progression from isolated bony injuries (type A) to fracture dislocations (type C).MethodsA total of 275 AO Spine members participated in a validation aimed at classifying 25 upper cervical spine injuries through computed tomography scans according to the AO Spine Upper Cervical Classification System. The validation occurred on two separate occasions, three weeks apart. Descriptive statistics for percent agreement with the gold-standard were calculated and the Pearson χ 2 test evaluated significance between validation groups. Kappa coefficients (κ) determined the interobserver reliability and intraobserver reproducibility.ResultsThe accuracy of AO Spine members to appropriately classify upper cervical spine injuries was 79.7% on assessment 1 (AS1) and 78.7% on assessment 2 (AS2). The overall intraobserver reproducibility was substantial (κ=0.70), while the overall interobserver reliability for AS1 and AS2 was substantial (κ=0.63 and κ=0.61, respectively). Injury location had higher interobserver reliability (AS1: κ = 0.85 and AS2: κ=0.83) than the injury type (AS1: κ=0.59 and AS2: 0.57) on both assessments.ConclusionThe global validation of the AO Spine Upper Cervical Injury Classification System demonstrated substantial interobserver agreement and intraobserver reproducibility. These results support the universal applicability of the AO Spine Upper Cervical Injury Classification System.Level of evidence4.

Dataset Information

Tenosynovial giant cell tumours of the upper and lower cervical spine: two case reports.

Introduction

Case presentation

Discussion

Publications

Tenosynovial giant cell tumours of the upper and lower cervical spine: two case reports.

Similar Datasets

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