Implementation of a dual platelet inventory in a tertiary hospital during the COVID-19 pandemic enabling cold-stored apheresis platelets for treatment of actively bleeding patients.

ABSTRACT:

Background

To increase preparedness and mitigate the risk of platelet shortage without increasing the number of collections, we introduced a dual platelet inventory with cold-stored platelets (CSP) with 14-days shelf life for actively bleeding patients during the COVID-19 pandemic.

Study design and methods

We collected apheresis platelet concentrates with blood type O or A. All patients receiving CSP units were included in a quality registry. Efficacy was evaluated by total blood usage and laboratory analysis of platelet count, hemoglobin, and TEG 6s global hemostasis assay. Feasibility was evaluated by monitoring inventory and a survey among laboratory staff.

Results

From 17 March, 2020, to 31 December, 2021, we produced 276 CSP units and transfused 186 units to 92 p

SUBMITTER: Braathen H 

PROVIDER: S-EPMC9349781 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature