Management of suspected and confirmed COVID-19 (SARS-CoV-2) vaccine hypersensitivity.

ABSTRACT:

Background

Systemic allergic reactions to vaccines are very rare. In this study we assessed the management and outcome of suspected SARS-CoV-2 vaccine hypersensitivity.

Methods

Totally, 334 individuals underwent an allergy work up regarding SARS-CoV-2 vaccination (group A: 115 individuals suspected to be at increased risk for vaccine-related reactions before vaccination and group B: 219 patients with reactions after COVID vaccination). The large majority of the SPT/IDT with the vaccines were negative; however, we identified in 14.1% (n = 47) a possible sensitization to the SARS-CoV-2 vaccine and/or its ingredients defined as one positive skin test. Of the 219 individuals (group B) who experienced symptoms suspicious for a hypersensitivity reaction after vaccination, 214 were

SUBMITTER: Worm M 

PROVIDER: S-EPMC9350006 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature