Recombinant protein subunit COVID-19 vaccine-induced Guillain-Barre Syndrome in an adolescent: A case report.

ABSTRACT: Guillain-Barré Syndrome (GBS), an autoimmune neurological disease of peripheral nerves, has been causally associated with COVID-19 vaccination in adults. However, no such report has been published so far in children. We describe a 13-year-old female child who presented to the emergency department with complaints of bilateral upper limb, lower limb and truncal weakness over 3 days following first dose of recombinant protein subunit COVID-19 vaccine (Corbevax). Clinical examination and nerve conduction studies showed pure motor axonal polyneuropathy with absent compound muscle action potential (CMAP) in all sampled nerves of upper and lower limbs which was consistent with the diagnosis of GBS after ruling out possible alternative aetiologies. A temporal association between first dose of prot

SUBMITTER: Rohilla R 

PROVIDER: S-EPMC9350234 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature